
Microsoft has published a list of programs that are currently incompatible with Windows Vista SP1. "Service Pack 1 for Windows Vista is an important update for Windows Vista. Windows Vista Service Pack 1 (SP1) contains many security, reliability, and feature updates for Windows Vista. A program may experience a loss of functionality after you install Windows Vista SP1. However, most programs will continue to work as expected after you install Windows Vista SP1."
Windows Vista SP1 Incompatible Programs
Source: Techpowerup
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